Conan O’Brien Mourns the Loss of His Parents, Dr. Thomas O’Brien and Ruth Reardon O’Brien

Conan O’Brien is mourning the loss of his parents, Dr. Thomas O’Brien and Ruth Reardon O’Brien, who passed away within three days of each other in December 2024. Dr. Thomas O’Brien, a renowned epidemiologist and Harvard professor, died at 95 on December 9, while Ruth, a trailblazing lawyer, passed away at 92 on December 12. The couple, married for 66 years, were remembered for their remarkable careers and dedication to their family.

Dr. Thomas O’Brien was a pioneer in infectious diseases, serving as the first director of the infectious diseases division at Brigham and Women’s Hospital in Boston. He was known for his early warnings about antimicrobial resistance and his global efforts to combat infectious diseases. Conan described his father as a “dreamer” with an insatiable curiosity and a love for humor, often being the “funniest guy in the room.” He credited his father with instilling in him a love for travel and comedy, recalling a memorable trip through South America during his childhood.

Ruth Reardon O’Brien was a trailblazer in the legal field, becoming one of the first women to make partner at the prestigious Boston law firm Ropes & Gray. She balanced her demanding career with raising six children, earning Conan’s admiration for her “heroic” efforts. He described her as a “realist” who ensured the family was well cared for while excelling in her profession. Ruth was also known for her compassion, often helping neighbors with their legal issues.

Conan reflected on their enduring partnership, calling them “kindred spirits” who complemented each other perfectly. Despite their demanding careers, they created a loving and chaotic household filled with laughter and support. The couple is survived by their six children and nine grandchildren.

The deaths of Conan’s parents came during a challenging period for the comedian, who is preparing to host the 2025 Oscars. He has been open about the emotional toll of their passing, describing it as a time to take things “a day at a time.” Conan’s tribute to his parents highlighted their profound impact on his life and career, celebrating their legacy of hard work, humor, and compassion.

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